
产品货号:
Z35572
中文名称:
NEDD4L抗体
英文名称:
Anti-NEDD4L Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-NEDD4L Antibody |
指标别名 | hNedd4 2;KIAA0439;NEDD4 2;NEDD4.2;NEDD4L;NEDL3;RSP5 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IP |
基因名称 | NEDD4L |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human NEDD4-2 |
实际分子量 | 130KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Neural precursor cell expressed developmentally downregulated gene 4-like (NEDD4L) or NEDD4-2 (NEDD4-2) is an enzyme (ubiquitin ligase) of the NEDD4 family.This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases.HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates,thus targeting specific proteins for lysosomal degradation.The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel,ENaC.Single nucleotide polymorphisms in this gene may be associated with essential hypertension.Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Uniprot ID | Q96PU5 |
基因名全称 | E3 ubiquitin-protein ligase NEDD4-like |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunocoprecipitation 1:20 |
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